For hunting I’ve found that large slow moving rounds, .50 muzzleloader or .45-70 in particular, kill quickly with almost no damage to the meat. While a fast moving smaller caliber, .223, .243, .30-‘06, .300Win, etc., damage (bloodshot) far more meat than the large slow movers and don’t kill any quicker.
That being said I only hunt with 30-‘06 or .223 these days. Neck shots being my intention it doesn’t make much difference, IMO.